Schizophrenia

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  • Patient's perspective: A Beautiful Mind (the...

    About.com Schizophrenia: Most Popular Articles
    15 Sep 2014 | 6:30 am
    A patient's perspective: A Beautiful Mind, the movie
  • The Positive and Negative Symptoms of...

    About.com Schizophrenia: Most Popular Articles
    15 Sep 2014 | 6:30 am
    Are you having experiences that seem unreal? Are you concerned about strange behavior in a loved one? Learn to understand and describe the symptoms of schizophrenia, so that you can communicate them to a doctor.
  • Schizophrenia more like an 'orchestra' of disorder

    Schizophrenia News
    15 Sep 2014 | 10:36 pm
    ELEANOR HALL: Now to that research on schizophrenia that indicates it's not a single disease, but a group of eight genetically-distinct disorders. The study is published in the American Journal of Psychiatry and the researchers say their findings should lead to improved diagnosis and treatment for the debilitating mental illness.
  • Is Medical Marijuana Destined to Become a Top Schizophrenia Treatment?

    Schizophrenia News
    13 Sep 2014 | 11:24 am
    One of the most contentious debates surrounding medical marijuana is whether its use could help millions of people suffering from schizophrenia. For decades, the conventional wisdom has been that marijuana, at a minimum, triggers the disease, or at a maximum, causes it.
  • Schizophrenia 'made up of eight specific genetic disorders'

    Schizophrenia News From Medical News Today
    15 Sep 2014 | 8:00 am
    Schizophrenia is not an individual condition but is made up of eight genetically distinct disorders, according to a new study by researchers at Washington University in St. Louis.
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    Schizophrenia News

  • Schizophrenia more like an 'orchestra' of disorder

    15 Sep 2014 | 10:36 pm
    ELEANOR HALL: Now to that research on schizophrenia that indicates it's not a single disease, but a group of eight genetically-distinct disorders. The study is published in the American Journal of Psychiatry and the researchers say their findings should lead to improved diagnosis and treatment for the debilitating mental illness.
  • Schizophrenia is eight different diseases, not one

    14 Sep 2014 | 9:47 pm
    New research shows that schizophrenia is not a single disease, but a group of eight distinct disorders, each caused by changes in clusters of genes that lead to different sets of symptoms. The finding sets the stage for scientists to develop better ways to diagnose and treat schizophrenia, a mental illness that can be devastating when not adequately managed, says C. Robert Cloninger, co-author of the study published today in the American Journal of Psychiatry.
  • Schizophrenia is eight different diseases, not one

    14 Sep 2014 | 9:47 pm
    New research shows that schizophrenia is not a single disease, but a group of eight distinct disorders, each caused by changes in clusters of genes that lead to different sets of symptoms. Schizophrenia is eight different diseases, not one New research shows that schizophrenia is not a single disease, but a group of eight distinct disorders, each caused by changes in clusters of genes that lead to different sets of symptoms.
  • VIDEO: Family faces tragedy of losing son to suicide

    13 Sep 2014 | 11:52 pm
    DOUG MCSWANE, FATHER, looks at a photo of his son, Patrick, who was schizophrenic and committed suicide. EDITOR'S NOTE: These are the first articles in a series on the role of the church in addressing mental illness.
  • Is Medical Marijuana Destined to Become a Top Schizophrenia Treatment?

    13 Sep 2014 | 11:24 am
    One of the most contentious debates surrounding medical marijuana is whether its use could help millions of people suffering from schizophrenia. For decades, the conventional wisdom has been that marijuana, at a minimum, triggers the disease, or at a maximum, causes it.
 
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    MedWorm: Schizophrenia

  • Schizophrenia is actually eight disorders, not one disease

    15 Sep 2014 | 2:44 pm
    Brooks HaysST. LOUIS, Sept. 15 (UPI) -- Schizophrenia isn't a single disease but eight distinct disorders, each with their own genetic footprint. (Source: Health News - UPI.com)MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
  • Art that sheds light on schizophrenia

    14 Sep 2014 | 10:20 pm
    Using images from medical science, artist Susan Aldworth has used her work to raise questions about human identity, says Hilly Janes (Source: Telegraph Health)
  • Schizophrenia not a single disease but multiple genetically distinct disorders

    14 Sep 2014 | 8:00 pm
    (Washington University School of Medicine) New research shows that schizophrenia isn't a single disease but a group of eight genetically distinct disorders, each with its own set of symptoms. The finding could be a first step toward improved diagnosis and treatment for the debilitating psychiatric illness.The research at Washington University School of Medicine in St. Louis is reported online Sept. 15 in the American Journal of Psychiatry. (Source: EurekAlert! - Medicine and Health)
  • Brain Development in Schizophrenia Strays from the Normal Path

    14 Sep 2014 | 8:00 pm
    (Elsevier) Schizophrenia is generally considered to be a disorder of brain development and it shares many risk factors, both genetic and environmental, with other neurodevelopmental disorders such as autism and intellectual disability. (Source: EurekAlert! - Biology)
  • Predictions, perception, and a sense of self

    14 Sep 2014 | 4:00 pm
    In recent years there has been a paradigm shift in theoretical neuroscience in which the brain—as a passive processor of sensory information—is now considered an active organ of inference, generating predictions and hypotheses about the causes of its sensations. In this commentary, we try to convey the basic ideas behind this perspective, describe their neurophysiologic underpinnings, and highlight the potential importance of this formulation for clinical neuroscience. The formalism it provides—and the implementation of active inference in the brain—may have the…
 
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    About.com Schizophrenia: What's Hot Now

  • How Schizophrenia Is Diagnosed

    schizophrenia.guide@about.com
    15 Sep 2014 | 4:24 am
    The better you understand the language and the process of diagnosing schizophrenia, the better you can communicate with your doctor. Remember that only a psychologist or psychiatrist can rule out or diagnose schizophrenia.
  • Who Gets Schizophrenia?

    schizophrenia.guide@about.com
    15 Sep 2014 | 4:24 am
    Although the overall incidence of schizophrenia in the United States is close to 1%, different groups have a greater or lesser likelihood of developing the illness. This article from your About Guide to Schizophrenia reviews the incidence of schizophrenia among different groups of people, which scientists are using as clues to help find the cause.
  • Living With Schizophrenia

    schizophrenia.guide@about.com
    15 Sep 2014 | 4:24 am
    Schizophrenia is a chronic disease, and you should plan for times of remission and times of relapse. Even in remission, your residual symptoms (the symptoms you continue to have even when you’re relatively well) will effect all aspects of your life. This article from your About Guide to Schizophrenia gives you concrete suggestions to help you improve you independent living skills and social relationships. Page 2.
  • Schizophrenia Early Diagnosis

    schizophrenia.guide@about.com
    15 Sep 2014 | 4:24 am
    How early can schizophrenia be diagnosed? Are there warning signs that can guide prevention, early diagnosis and treatment?
  • The Difference between Schizophrenia and...

    schizophrenia.guide@about.com
    15 Sep 2014 | 4:24 am
    Schizophrenia and schizoaffective are two different disorders. This article discusses the relevant differences why that matters.
 
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    Schizophrenia Bulletin - Advance Access

  • Comparing Fractional Anisotropy in Patients With Childhood-Onset Schizophrenia, Their Healthy Siblings, and Normal Volunteers Through DTI

    Moran, M. E., Luscher, Z. I., McAdams, H., Hsu, J. T., Greenstein, D., Clasen, L., Ludovici, K., Lloyd, J., Rapoport, J., Mori, S., Gogtay, N.
    12 Sep 2014 | 12:27 am
    Background: Diffusion tensor imaging is a neuroimaging method that quantifies white matter (WM) integrity and brain connectivity based on the diffusion of water in the brain. White matter has been hypothesized to be of great importance in the development of schizophrenia as part of the dysconnectivity model. Childhood-onset schizophrenia (COS), is a rare, severe form of the illness that resembles poor outcome adult-onset schizophrenia. We hypothesized that COS would be associated with WM abnormalities relative to a sample of controls. Methods: To evaluate WM integrity in this population 39…
  • Evidence That Environmental and Genetic Risks for Psychotic Disorder May Operate by Impacting on Connections Between Core Symptoms of Perceptual Alteration and Delusional Ideation

    Smeets, F., Lataster, T., Viechtbauer, W., Delespaul, P., G.R.O.U.P.
    12 Sep 2014 | 12:27 am
    Background: Relational models of psychopathology propose that symptoms are dynamically connected and hypothesize that genetic and environmental influences moderate the strength of these symptom connections. Previous findings suggest that the interplay between hallucinations and delusions may play a crucial role in the development of psychotic disorder. The current study examined whether the connection between hallucinations and delusions is impacted by proxy genetic and environmental risk factors. Methods: Hallucinations and delusions at baseline and at 3-year follow-up were assessed in a…
  • Aberrant Current Source-Density and Lagged Phase Synchronization of Neural Oscillations as Markers for Emerging Psychosis

    Ramyead, A., Kometer, M., Studerus, E., Koranyi, S., Ittig, S., Gschwandtner, U., Fuhr, P., Riecher-Rossler, A.
    9 Sep 2014 | 11:57 pm
    Background:Converging evidence indicates that neural oscillations coordinate activity across brain areas, a process which is seemingly perturbed in schizophrenia. In particular, beta (13-30 Hz) and gamma (30–50 Hz) oscillations were repeatedly found to be disturbed in schizophrenia and linked to clinical symptoms. However, it remains unknown whether abnormalities in current source density (CSD) and lagged phase synchronization of oscillations across distributed regions of the brain already occur in patients with an at-risk mental state (ARMS) for psychosis. Methods:To further elucidate…
  • Schizophrenia and Autism as Contrasting Minds: Neural Evidence for the Hypo-Hyper-Intentionality Hypothesis

    Ciaramidaro, A., Bolte, S., Schlitt, S., Hainz, D., Poustka, F., Weber, B., Bara, B. G., Freitag, C., Walter, H.
    9 Sep 2014 | 11:57 pm
    Both schizophrenia (SCZ) and autism spectrum disorder (ASD) are characterized by mentalizing problems and associated neural dysfunction of the social brain. However, the deficits in mental state attribution are somehow opposed: Whereas patients with SCZ tend to over-attribute intentions to agents and physical events ("hyper-intentionality"), patients with autism treat people as devoid of intentions ("hypo-intentionality"). Here we aimed to investigate whether this hypo-hyper-intentionality hypothesis can be supported by neural evidence during a mentalizing task. Using functional magnetic…
  • Regressing to Prior Response Preference After Set Switching Implicates Striatal Dysfunction Across Psychotic Disorders: Findings From the B-SNIP Study

    Hill, S. K., Reilly, J. L., Ragozzino, M. E., Rubin, L. H., Bishop, J. R., Gur, R. C., Gershon, E. S., Tamminga, C. A., Pearlson, G. D., Keshavan, M. S., Keefe, R. S. E., Sweeney, J. A.
    5 Sep 2014 | 11:12 pm
    Difficulty switching behavioral response sets is established in psychotic disorders. In rodent models, prefrontal lesions cause difficulty initially switching to new response sets (perseverative errors) while striatal lesions cause difficulty suppressing responses to previous choice preferences (regressive errors). Studies of psychotic disorders have not previously assessed these 2 error types. Bipolar and Schizophrenia Network on Intermediate Phenotypes (B-SNIP) participants included probands with schizophrenia (N = 212), psychotic bipolar (N = 192), and schizoaffective disorder (N = 131),…
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    Schizophrenia Society of Saskatchewan

  • SSS 2014 Annual General Meeting

    Schizophrenia Society of Saskatchewan
    11 Sep 2014 | 7:54 am
    You are invited to attend the Provincial Office of the Schizophrenia Society of Saskatchewan’s Annual General Meeting and Awards Luncheon Monday, September 29, 2014 11:30 a.m. – 2:00 p.m. DoubleTree by Hilton Regina Hotel and Conference Centre Swift Current Room *Please RSVP your attendance for lunch by September 26th.  Please return the attached form or by calling the SSS office at 306-584-2620 or 1-877-584-2620 or by fax at 306-584-0525 or by e-mail to sssprov@sasktel.net
  • Regina Chapter 2014 Annual General Meeting

    Schizophrenia Society of Saskatchewan
    11 Sep 2014 | 7:52 am
    Annual General Meeting The Regina Chapter of The Schizophrenia Society of Saskatchewan (SSS) Monday, September 15, 2014 Meet and greet at 6:15pm (light supper) Meeting at 7:00 pm *Please RSVP to the contact info below United Way of Regina 1440 Scarth Street Guest Speakers Anita Hopfauf- SSS Executive Director Tanya Condo-SSS Partnership Program Coordinator *The Regina Chapter is currently looking for new Board Members.  If you are interested, please email your resume to Regina Chapter President, Mike Gardiner at carmi@sasktel.net or call 306 584-2620 to leave a message.
  • Family Members and Caregiver’s Survey

    Schizophrenia Society of Saskatchewan
    17 Jul 2014 | 12:42 pm
    Are you a family member or caregiver to someone with schizophrenia,bipolar disorder, or other related mental illness? The Schizophrenia Society of Canada is doing research into the experiences of caregivers, and would like your feedback. If you are interested in taking part in this very important research, please click here to proceed to the Schizophrenia Society of Canada research page. Thank you for time and insight!
  • SSC Award Applications are now being accepted – Deadline is September 12, 2014

    Schizophrenia Society of Saskatchewan
    17 Jul 2014 | 12:37 pm
    The Schizophrenia Society of Canada is now accepting applications for their annual awards. Click here to learn more!
  • Schizophrenia Society Annual Awards – Nomination Forms

    Schizophrenia Society of Saskatchewan
    22 Jun 2014 | 2:33 pm
    The Schizophrenia Society of Saskatchewan will be handing out awards again this year September our AGM (date pending). If you are interested in nominating someone for any of the following awards, please download the appropriate form and return it to the Schizophrenia Society of Saskatchewan by Monday, July 28th, 2014. Schizophrenia Society of Saskatchewan Award Nomination Form 2014 Community Spirit Award - This award recognizes a business, corporation or organization for their outstanding community spirit in supporting the SSS in their mission to improve the quality of life of those affected…
 
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    Schizophrenia News -- ScienceDaily

  • Brain development in schizophrenia strays from normal path

    15 Sep 2014 | 5:37 am
    Schizophrenia is generally considered to be a disorder of brain development and it shares many risk factors, both genetic and environmental, with other neurodevelopmental disorders such as autism and intellectual disability. The normal path for brain development is determined by the combined effects of a complex network of genes and a wide range of environmental factors. However, longitudinal brain imaging studies in both healthy and patient populations are required in order to map the disturbances in brain structures as they emerge, researchers say.
  • Schizophrenia not a single disease but multiple genetically distinct disorders

    15 Sep 2014 | 5:35 am
    Schizophrenia isn’t a single disease but a group of eight genetically distinct disorders, each with its own set of symptoms, research shows. The finding could be a first step toward improved diagnosis and treatment for the debilitating psychiatric illness.
  • Neurochemical imbalance in schizophrenia discovered

    11 Sep 2014 | 9:42 am
    Using human induced pluripotent stem cells (hiPSCs), researchers have discovered that neurons from patients with schizophrenia secrete higher amounts of three neurotransmitters broadly implicated in a range of psychiatric disorders.
  • Is the pattern of brain folding a 'fingerprint' for schizophrenia?

    11 Sep 2014 | 6:29 am
    Anyone who has seen pictures or models of the human brain is aware that the outside layer, or cortex, of the brain is folded in an intricate pattern of “hills”, called gyri, and “valleys”, called sulci. It turns out that the patterns of cortical folding are largely consistent across healthy humans, broadly speaking. However, disturbances in cortical folding patterns suggest deeper disturbances in brain structure and function..
  • Risk of diabetes in children, adolescents exposed to antipsychotics: Danish 12-year case-control study

    2 Sep 2014 | 6:32 am
    Children and adolescents pegged with a psychiatric diagnosis had an increased risk of developing diabetes if they were exposed to antipsychotics. Using data from the nationwide Danish registers, a group of researchers studied 48,299 children and adolescents with psychiatric disorders to document the frequency and possible predictors of type II diabetes, defined by treatment with an oral antidiabetic drug.
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    Schizophrenia Society of Nova Scotia

  • Families Matter in Mental Health: An Education and Support Program -- Halifax Regional Municipality

    16 Sep 2014 | 4:00 am
    DartmouthBegins TODAY, September 16th, 6:30 pmSackvilleOngoing until December 8th, 2014 Please click on the image to magnify it.To download a PDF version of the above flyer, please click here.To download the Families Matter in Mental Health provincial brochure (PDF), please click here.Also see:Supporting Families in Recovery - Capital Health Addictions and Mental Health ProgramFamilies Matter in Mental Health: An Education and Support Program -- Nova Scotia
  • Lunenburg County Chapter of the SSNS

    15 Sep 2014 | 3:30 am
    Tomorrow, September 16th, 7:00 pmThe Lunenburg County Chapter holds monthly support meetings for people living with mental illness, their family members, and friends, at Holy Trinity Anglican Church, 68 Alexandra Avenue, Bridgewater.  Meetings are held the third Tuesday of every month, except during the summer months of July and August. For further information please call (902) 527-1893 or (902) 527-1692 or visit ssnslcc.blogspot.com.
  • Cumberland County Chapter of the SSNS

    15 Sep 2014 | 3:00 am
    Tomorrow, September 16th, 7:00 pmCumberland County Chapter meetings are held the third Tuesday of each month, beginning at 7:00 pm, in the Dr. Carson & Marion Murray Community Centre, 6 Main Street, Springhill, Nova Scotia. Meetings are not held during the months of July and August.Photograph courtesy of the Town of Springhill.
  • Kings County Chapter of the SSNS

    15 Sep 2014 | 2:30 am
    This Wednesday, September 17th, 7:00 pm Meetings of the Kings County Chapter of the Schizophrenia Society of Nova Scotia are generally held the third Wednesday of each month, beginning at 7:00 pm, at the Louis Millet Community Complex, Room 121 (east entrance), 9489 Commercial Street, New Minas, Nova Scotia. Meetings are not held during the summer months of July and August.  To contact the Kings County Chapter, please send an email to kcschizsoc@outlook.com.Also see: Kings County Chapter of the SSNSKings County Chapter brochure (PDF) Support for Family and Friends of Persons Living with…
  • The "From Recovery to Discovery" Mental Health Peer Support Group - Halifax

    15 Sep 2014 | 2:00 am
    This Thursday, September 18th, 6:30 pmMeetingsEvery Thursday Evening6:30 pm to 8:30 pmCommunity RoomAtlantic Superstore – Barrington Street 1075 Barrington StreetHalifax, Nova Scotia Plenty of free parking!The Atlantic Superstore – Barrington Street is on the 3, 7, 9, and 41 Metro Transit bus routes.The From Recovery to Discovery Mental Health Peer Support Group is open to anyone affected by any type of mental illness, and this includes family members and friends.Free! Thursday, September 18th, 2014, 6:30 pmA Mental Health Peer Support Group MeetingTopic: To Be AnnouncedPhoto…
 
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    schizophrenic.com

  • Brain 'folding' pattern could suggest disturbances linked to schizophrenia

    M Tyler
    12 Sep 2014 | 9:22 am
    The outside layer of the human brain is folded into a hill-and-valley pattern called gyri (hills) and sulci, (valleys). The way this pattern looks tends to be uniform in healthy brains, but differences in how this outer layer, the cortex, is structured, could helps scientists understand more about schizophrenia. A new study published in Biological Psychiatry found that changes in folding patterns could cause deficits in structural connections of the brain. "The cortical folding pattern itself may not be so important, but the disturbances in connections between brain regions implicated by the…
  • Obsessive-complusive disorder increases risk for schizophrenia

    M Tyler
    9 Sep 2014 | 9:08 am
    Individuals with obsessive-compulsive disorder (OCD) may have a higher risk for schizophrenia, according to a new study. Danish researchers analyzed data on 3 million people who were born between 1955 and 2006. Of the 16,200 people in the study who developed schizophrenia, about 3 percent of them had a previous diagnosis of OCD. "In the general population, about 1 percent of people are diagnosed with schizophrenia - a proportion that jumps to 2 percent among those who already have a diagnosis of OCD," Dr. Alan Manevitz, who was not involved in the study, said in an article on U.S. News &…
  • Antipsychotic exposure during childhood could increase diabetes risk

    M Tyler
    2 Sep 2014 | 10:30 am
    Children who take antipsychotic medications may have an increased risk of developing diabetes, according to a study published in the Journal of the American Academy of Child and Adolescent Psychiatry. Researchers studied a group of 48,299 children and adolescents with psychiatric disorders, documenting the potential predictors of type 2 diabetes. Results showed that absolute diabetes risk in youth who had been exposed to antipsychotic medications was approximately 0.72 percent compared to 0.27 percent in those youth who weren't exposed to these types of medications. The study also showed that…
  • Schizophrenia risk doubles with vitamin D deficiency

    M Tyler
    26 Aug 2014 | 11:24 am
    Seventy-five percent of Americans have double the risk of schizophrenia due to vitamin D deficiency, according to a study published in the Journal of Clinical Endocrinology & Metabolism. Researcher Ahmad Esmaillzadeh, from Isfahan University of Medical Sciences, found that people with schizophrenia have lower vitamin D levels than healthy individuals. Other studies have shown that the disease is more common in colder climates, where sunlight is more scarce. “This is the first comprehensive meta-analysis to study the relationship between [vitamin D deficiency and schizophrenia],”…
  • Alkermes submits applications for schizophrenia drug aripiprazole

    M Tyler
    25 Aug 2014 | 8:46 am
    Biopharmaceutical company Alkermes plc announced today that it has submitted a New Drug Application to the FDA for approval of aripiprazole, a long-acting injectable schizophrenia medication. The drug is a once-monthly antipsychotic that, according to the company, was able to cause significant improvements in schizophrenia symptoms during a phase 3 study that assessed the efficacy and safety of aripiprazole. "Aripiprazole lauroxil was generally well tolerated in the study, and the observed safety profile of aripiprazole lauroxil was similar to that reported with oral aripiprazole," RTT News…
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    Schiz Life

  • Amy’s Story: Living with Schizophrenia

    Schiz Life
    6 Sep 2014 | 4:45 pm
    The following is a post by our friend Amy Kay, who has begun, recently and courageously, to voice and share her experiences with schizophrenia on her blog Voice of a Schizophrenic.  We are happy to share her story.. I used to tell people “I have a bad brain.” I am not going to say I suffer from schizophrenia but rather I endure and cope with it. My name is Amy Kay and I have schizophrenia. I do not want to hurt others or myself. Neither do I hear voices and I no longer live in a delusional world. In 2008 during my initial psychiatric breakdown it started with a state of euphoria.
  • New Schizophrenia Dimmer Switch Medication Concept

    Schiz Life
    12 Aug 2014 | 12:51 pm
    As we all know, schizophrenia medication can cause a rash of ill effects in it’s users, often times to the point that the disruption from the medication is subjectively worse than the symptoms of the illness they are meant to treat.  Finding the right balance of medications to properly treat the problem without creating addition side effects can be a long and drawn out process that is frustrating to the patient and the doctor.  However, a breakthrough in this process may have just occurred… Yesterday, the Monash University in Melbourne, Australia published its findings (read the…
  • The 12 Core Functions: Your Therapist and Treatment Path

    Schiz Life
    20 Jul 2014 | 5:43 am
    The 12 Core Functions: Your Therapist and Treatment Path A sad reality is that many people dealing with the symptoms of schizophrenia simply fail to receive treatment.  There are lots of various reasons why this can happen, but one of the reasons is a resistance and fear in not understanding how treatment will transpire.  This article is meant to give the reader a general overview of what the therapist is thinking and the guidelines they follow to perform their task.  Your treatment will be personalized and tailored specifically to your experiences, symptoms, and receptiveness, but it will…
  • Schizophrenia Spectrum Disorders

    Schiz Life
    25 May 2014 | 1:52 pm
    What is schizophrenia spectrum disorder? How is it diagnosed and treated? A better understanding of this disorder might be derived from an understanding of the terms used to identify it. Schizophrenia is a mental disorder characterized by reduced emotional expression, abnormal social behavior and the inability to distinguish what is real and what isn’t. Persons with schizophrenia might talk about hearing voices, experience hallucinations, and suffer delusions. Spectrum refers to a range of linked conditions sometimes extending to include singular symptoms and disorders, as they relate…
  • Schizophrenia Risk Factors

    Schiz Life
    25 May 2014 | 1:39 pm
    Schizophrenia is a chronic mental disorder that adversely affects about 1 per cent of the global population. It is commonly described as someone being delusional, paranoid, and hallucinating, but that’s only one type of schizophrenia. Schizophrenia can occur at any age, but it tends to first progress between adolescence and early adulthood, normally between the ages of 16 – 30 years. It rarely occurs before adolescence or after age 45. It is more likely to worsen if left untreated. The illness itself cannot be cured but with sufficient medication, the symptoms can be controlled.
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