Schizophrenia

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    schizophrenia - Google News

  • Intra-Cellular Commences Phase III Schizophrenia Study - Zacks.com

    26 Nov 2014 | 12:51 pm
    Intra-Cellular Commences Phase III Schizophrenia StudyZacks.comIntra-Cellular Therapies, Inc. (ITCI - Snapshot Report) announced that it has enrolled the first patient in a randomized, double-blind, placebo-controlled phase III study (ITI-007-301) on its lead candidate, ITI-007, for the treatment of schizophrenia Intra-Cellular Commences Phase III Schizophrenia Study - Analyst BlogNasdaqall 3 news articles »
  • Study finds some schizophrenics do well without long-term antipsychotics - Chicago Tribune

    26 Nov 2014 | 9:13 am
    Study finds some schizophrenics do well without long-term antipsychoticsChicago TribuneThe conventional wisdom is that people diagnosed with schizophrenia, the most severe and disabling mental illness, need to keep taking powerful antipsychotic medications to avoid disastrous relapses. That's the message stressed by the American ...
  • Police: Rochester man who killed daughter, self had schizophrenia - Austin Herald

    26 Nov 2014 | 8:32 am
    KAREPolice: Rochester man who killed daughter, self had schizophreniaAustin HeraldROCHESTER — A divorced father who fatally shot his visiting 9-year-old daughter and then turned the handgun on himself over the weekend in his Rochester home had been struggling for years with psychological problems, police said Tuesday. Bradley J.Funeral services set for shooting victimKIMT 3Father and daughter found dead in northwest Rochester home identifiedKTTCVictims of Apparent Murder-Suicide IdentifiedKAALtv.comall 76 news articles »
  • Schizophrenia Study Finds New Genetic Links - Discover Magazine

    26 Nov 2014 | 8:00 am
    Discover MagazineSchizophrenia Study Finds New Genetic LinksDiscover MagazineSchizophrenia, which affects 1 in 100 people worldwide and an estimated 2.4 million Americans, exacts tremendous social costs and great human suffering. Drugs can calm the inner voices, delusions and hallucinations, but few patients recover fully, and ...
  • Chronic Or Permanent Stress Can Result In Mental Disorders Such As ... - Medical Daily

    25 Nov 2014 | 8:16 am
    Medical DailyChronic Or Permanent Stress Can Result In Mental Disorders Such As Medical Daily“We studied only one part of the brain, the hippocampus, but our findings could provide insight into how white matter is changing in conditions such as schizophrenia, autism, depression, suicide, ADHD and PTSD,” lead researcher Daniela Kaufner said in and more »
 
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    Schizophrenia News

  • Neurodevelopmental and environmental hypotheses of negative symptoms of schizophrenia.

    21 Nov 2014 | 6:13 am
    The negative symptoms of schizophrenia, avolition, alogia, apathy and impaired or nonexistent social functioning, are strongly correlated with the progressive course and long-term prognosis of the disease, undermining the patient's ability to integrate socially, interpersonal skills and quality of life. At a time when new drug strategies are being developed, a better understanding of the etiology and pathogenesis underpinning the occurrence of negative symptoms constitutes an essential prerequisite for real therapeutic advances.
  • New Drug Application Submitted to FDA for 3-Month Paliperidone...

    19 Nov 2014 | 7:15 pm
    A new drug application has been submitted to the FDA for a 3-month formulation of the atypical antipsychotic agent paliperidone palmitate . The NDA seeks approval for the medication as a treatment for schizophrenia in adults.
  • Janssen announces submission of NDA for three-month paliperidone palmitate

    19 Nov 2014 | 3:02 pm
    Janssen Research & Development, LLC today announced the submission of a New Drug Application for three-month atypical antipsychotic paliperidone palmitate to the U.S. Food and Drug Administration . The NDA seeks approval for the medication as a treatment for schizophrenia in adults.
  • Janssen announces submission of NDA for three-month paliperidone palmitate

    19 Nov 2014 | 12:34 pm
    Janssen Research & Development, LLC today announced the submission of a New Drug Application for three-month atypical antipsychotic paliperidone palmitate to the U.S. Food and Drug Administration . The NDA seeks approval for the medication as a treatment for schizophrenia in adults.
  • Court Report - November 2014 #2

    19 Nov 2014 | 9:59 am
    AstraZeneca Pharmaceuticals LP et al. v. Pharmadax USA, Inc. et al. 1:14-cv-07105; filed November 3, 2014 in the District Court of New Jersey Infringement of U.S. Patent No.
 
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    About.com Schizophrenia: What's Hot Now

  • What Causes Schizophrenia?

    schizophrenia.guide@about.com
    26 Nov 2014 | 3:20 am
    Schizophrenia is a complex disease of the brain. Although scientists continue to learn about schizophrenia, the exact cause of the illness is still not known. This article from your About Guide to Schizophrenia explains the current understanding about the causes of schizophrenia.
  • Schizophrenia Symptoms and Diagnosis

    schizophrenia.guide@about.com
    26 Nov 2014 | 3:20 am
    What are the main symptoms of schizophrenia? How is a diagnosis of schizophrenia made?
  • Schizophrenia Early Diagnosis

    schizophrenia.guide@about.com
    26 Nov 2014 | 3:20 am
    How early can schizophrenia be diagnosed? Are there warning signs that can guide prevention, early diagnosis and treatment?
  • What Do Hallucinations Feel Like in Schizophren...

    schizophrenia.guide@about.com
    26 Nov 2014 | 3:20 am
    Hallucinations are part of schizophrenia. This article focuses on what experiencing hallucinations feels like from a patient's perspective.
  • The Positive and Negative Symptoms of...

    schizophrenia.guide@about.com
    26 Nov 2014 | 3:20 am
    Are you having experiences that seem unreal? Are you concerned about strange behavior in a loved one? Learn to understand and describe the symptoms of schizophrenia, so that you can communicate them to a doctor.
 
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    About.com Schizophrenia: Most Popular Articles

  • Choosing Antipsychiotics

    26 Nov 2014 | 5:23 am
    How do you choose between the different antipsychotic medications?
  • The Positive and Negative Symptoms of...

    26 Nov 2014 | 5:23 am
    Are you having experiences that seem unreal? Are you concerned about strange behavior in a loved one? Learn to understand and describe the symptoms of schizophrenia, so that you can communicate them to a doctor.
  • What It's Like to Have Schizophrenia

    26 Nov 2014 | 5:23 am
    In schizophrenia, the most basic processes of perceiving and thinking are affected by the illness. Whether you want your loved ones to understand you better, are concerned for someone who's ill, or are simply curious, this article describes the internal experience of delusions, hallucinations, and more.
  • A list of UK, Australia, and Worldwide...

    26 Nov 2014 | 5:23 am
    Looking for educational resources, information about local support groups or ongoing research projects for schizophrenia? Here is a list of good UK, Australian and international resources to get you started.
  • What Causes Schizophrenia?

    26 Nov 2014 | 5:23 am
    Developmental theories of schizophrenia explore things that may have gone wrong during fetal and infant brain development.
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    Schizophrenia Bulletin - Advance Access

  • Antipsychotic Treatment and Mortality in Schizophrenia

    Torniainen, M., Mittendorfer-Rutz, E., Tanskanen, A., Bjorkenstam, C., Suvisaari, J., Alexanderson, K., Tiihonen, J.
    24 Nov 2014 | 12:24 am
    Background: It is generally believed that long-term use of antipsychotics increases mortality and, especially, the risk of cardiovascular death. However, there are no solid data to substantiate this view. Methods: We identified all individuals in Sweden with schizophrenia diagnoses before year 2006 (N = 21 492), aged 17–65 years, and persons with first-episode schizophrenia during the follow-up 2006–2010 (N = 1230). Patient information was prospectively collected through nationwide registers. Total and cause-specific mortalities were calculated as a function of cumulative…
  • The Importance of Talk Therapy

    Anonymous
    18 Nov 2014 | 8:08 am
  • Dopaminergic Circuitry and Risk/Reward Decision Making: Implications for Schizophrenia

    Stopper, C. M., Floresco, S. B.
    17 Nov 2014 | 10:55 pm
    Abnormal reinforcement learning and representations of reward value are present in schizophrenia, and these impairments can manifest as deficits in risk/reward decision making. These abnormalities may be due in part to dopaminergic dysfunction within cortico-limbic-striatal circuitry. Evidence from studies with laboratory animal have revealed that normal DA activity within different nodes of these circuits is critical for mediating dissociable processes that can refine decision biases. Moreover, both phasic and tonic dopamine transmission appear to play separate yet complementary roles in…
  • Are Negative Symptoms Dimensional or Categorical? Detection and Validation of Deficit Schizophrenia With Taxometric and Latent Variable Mixture Models

    Ahmed, A. O., Strauss, G. P., Buchanan, R. W., Kirkpatrick, B., Carpenter, W. T.
    14 Nov 2014 | 11:57 pm
    Studies have supported the validity of the deficit form of schizophrenia (ie, people with primary and enduring negative symptoms). A test of whether that group is a true taxon—that is, a distinct, discontinuous group—has yet to be conducted and the underlying structure of negative symptoms as categorical or dimensional remains undetermined. The present study examined the latent structure of negative and deficit symptoms to determine if a nonarbitrary boundary distinguishes deficit from nondeficit forms of schizophrenia (ie, whether these symptoms reflect a continuous or…
  • Early Intervention: How Early and With What?

    Carpenter, W. T., Buchanan, R. W.
    14 Nov 2014 | 11:51 pm
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    Schizophrenia Research

  • GABA receptor subunit distribution and FMRP–mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism

    S. Hossein Fatemi, Timothy D. Folsom
    24 Nov 2014 | 4:00 pm
    Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain. GABAergic receptor abnormalities have been documented in several major psychiatric disorders including schizophrenia, mood disorders, and autism. Abnormal expression of mRNA and protein for multiple GABA receptors has also been observed in multiple brain regions leading to alterations in the balance between excitatory/inhibitory signaling in the brain with potential profound consequences for normal cognition and maintenance of mood and perception.
  • Central executive network in young people with familial risk for psychosis — The Oulu Brain and Mind Study

    Tuomas Jukuri, Vesa Kiviniemi, Juha Nikkinen, Jouko Miettunen, Pirjo Mäki, Sari Mukkala, Jenni Koivukangas, Tanja Nordström, Juha Parkkisenniemi, Irma Moilanen, Jennifer H. Barnett, Peter B. Jones, Graham K. Murray, Juha Veijola
    21 Nov 2014 | 4:00 pm
    The central executive network controls and manages high-level cognitive functions. Abnormal activation in the central executive network has been related to psychosis and schizophrenia but it is not established how this applies to people with familial risk for psychosis (FR).
  • Risk-taking in schizophrenia and controls with and without cannabis dependence

    Bernard A. Fischer, Robert P. McMahon, Deanna L. Kelly, Heidi J. Wehring, Walter A. Meyer, Stephanie Feldman, William T. Carpenter, David A. Gorelick
    21 Nov 2014 | 4:00 pm
    Risk-based decision making is altered in people with schizophrenia and in people with cannabis use compared to healthy controls; the pattern of risk-assessment in people with co-occurring schizophrenia and cannabis dependence is poorly understood. This study examined measures of risk-taking and decision-making in people with and without schizophrenia and/or cannabis dependence.
  • The effect of lifetime adversities on resistance to antipsychotic treatment in schizophrenia patients

    Ahmed N. Hassan, Vincenzo De Luca
    21 Nov 2014 | 4:00 pm
    The aim of this study is to examine whether there is an association between cumulative life adversities and treatment-resistant schizophrenia.
  • Fronto-temporal transcranial Direct Current Stimulation (tDCS) reduces source-monitoring deficits and auditory hallucinations in patients with schizophrenia

    Marine Mondino, Frédéric Haesebaert, Emmanuel Poulet, Marie-Françoise Suaud-Chagny, Jérôme Brunelin
    20 Nov 2014 | 4:00 pm
    Auditory verbal hallucinations (AVH) in patients with schizophrenia have been associated with abnormal activity within the frontal and temporo-parietal areas (Jardri et al., 2011) and with a failure in source-monitoring processes (Frith, 1995; Waters et al., 2012). For instance, patients with AVH are more likely to confuse imagined and performed self-generated speech as revealed by the number of misattributions between words they were required to imagine saying (covert speech) and words they were required to say aloud (overt speech) during a source-monitoring task (Brunelin et al., 2006a).
 
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    Schizophrenia Research

  • GABA receptor subunit distribution and FMRP–mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism

    S. Hossein Fatemi, Timothy D. Folsom
    24 Nov 2014 | 4:00 pm
    Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain. GABAergic receptor abnormalities have been documented in several major psychiatric disorders including schizophrenia, mood disorders, and autism. Abnormal expression of mRNA and protein for multiple GABA receptors has also been observed in multiple brain regions leading to alterations in the balance between excitatory/inhibitory signaling in the brain with potential profound consequences for normal cognition and maintenance of mood and perception.
  • Central executive network in young people with familial risk for psychosis — The Oulu Brain and Mind Study

    Tuomas Jukuri, Vesa Kiviniemi, Juha Nikkinen, Jouko Miettunen, Pirjo Mäki, Sari Mukkala, Jenni Koivukangas, Tanja Nordström, Juha Parkkisenniemi, Irma Moilanen, Jennifer H. Barnett, Peter B. Jones, Graham K. Murray, Juha Veijola
    21 Nov 2014 | 4:00 pm
    The central executive network controls and manages high-level cognitive functions. Abnormal activation in the central executive network has been related to psychosis and schizophrenia but it is not established how this applies to people with familial risk for psychosis (FR).
  • Risk-taking in schizophrenia and controls with and without cannabis dependence

    Bernard A. Fischer, Robert P. McMahon, Deanna L. Kelly, Heidi J. Wehring, Walter A. Meyer, Stephanie Feldman, William T. Carpenter, David A. Gorelick
    21 Nov 2014 | 4:00 pm
    Risk-based decision making is altered in people with schizophrenia and in people with cannabis use compared to healthy controls; the pattern of risk-assessment in people with co-occurring schizophrenia and cannabis dependence is poorly understood. This study examined measures of risk-taking and decision-making in people with and without schizophrenia and/or cannabis dependence.
  • The effect of lifetime adversities on resistance to antipsychotic treatment in schizophrenia patients

    Ahmed N. Hassan, Vincenzo De Luca
    21 Nov 2014 | 4:00 pm
    The aim of this study is to examine whether there is an association between cumulative life adversities and treatment-resistant schizophrenia.
  • Fronto-temporal transcranial Direct Current Stimulation (tDCS) reduces source-monitoring deficits and auditory hallucinations in patients with schizophrenia

    Marine Mondino, Frédéric Haesebaert, Emmanuel Poulet, Marie-Françoise Suaud-Chagny, Jérôme Brunelin
    20 Nov 2014 | 4:00 pm
    Auditory verbal hallucinations (AVH) in patients with schizophrenia have been associated with abnormal activity within the frontal and temporo-parietal areas (Jardri et al., 2011) and with a failure in source-monitoring processes (Frith, 1995; Waters et al., 2012). For instance, patients with AVH are more likely to confuse imagined and performed self-generated speech as revealed by the number of misattributions between words they were required to imagine saying (covert speech) and words they were required to say aloud (overt speech) during a source-monitoring task (Brunelin et al., 2006a).
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    Schizophrenia News -- ScienceDaily

  • Schizophrenia may be triggered by excess protein during brain development

    24 Nov 2014 | 5:10 am
    A gene associated with schizophrenia plays a role in brain development and may help to explain the biological process of the disease, according to new research. Researchers saytoo much protein expressed by the NOS1AP gene, which has been associated with schizophrenia, causes abnormalities in brain structure and faulty connections between nerve cells that prevent them from communicating properly.
  • Mental disorders due to permanent stress?

    21 Nov 2014 | 5:29 am
    Activated through permanent stress, immune cells will have a damaging effect on and cause changes to the brain. This may result in mental disorders. Medical researchers are studying the effects of permanent stress on the immune system.
  • Helping patients with schizophrenia and their caregivers

    11 Nov 2014 | 2:02 pm
    Patients diagnosed with schizophrenia or schizoaffective disorder and their caregivers participated in 15 weekly one-hour sessions in a recent study. The treatment covered a range of topics and skills, including education about the illness, techniques to bolster family cohesion and adaptive use of religious coping, communication training, and problem-solving.
  • New knowledge about human brain's plasticity

    6 Nov 2014 | 10:18 am
    The brain's plasticity and its adaptability to new situations do not function the way researchers previously thought, according to a new study. Earlier theories are based on laboratory animals, but now researchers have studied the human brain, and reached some new conclusions.
  • Parasite-schizophrenia connection: One-fifth of schizophrenia cases may involve the parasite T. gondii

    29 Oct 2014 | 10:34 am
    Many factors, both genetic and environmental, have been blamed for increasing the risk of a diagnosis of schizophrenia. Some, such as a family history of schizophrenia, are widely accepted. Others, such as infection with Toxoplasma gondii, a parasite transmitted by soil, undercooked meat and cat feces, are still viewed with skepticism. A new study used epidemiological modeling methods to determine the proportion of schizophrenia cases that may be attributable to T. gondii infection. The work suggests that about one-fifth of cases may involve the parasite.
 
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    Schizophrenia Society of Nova Scotia

  • The "From Recovery to Discovery" Mental Health Peer Support Group - Halifax

    26 Nov 2014 | 4:00 am
    Tomorrow, November 27th, 6:30 pmMeetingsEvery Thursday Evening6:30 pm to 8:30 pmCommunity RoomAtlantic Superstore – Barrington Street 1075 Barrington StreetHalifax, Nova Scotia Plenty of free parking!The Atlantic Superstore – Barrington Street is on the 3, 7, 9, and 41 Metro Transit bus routes.The From Recovery to Discovery Mental Health Peer Support Group is open to anyone affected by any type of mental illness, and this includes family members and friends.Free! Thursday, November 27th, 2014, 6:30 pm Mental Health Peer Support Group Meeting Topic: To Be AnnouncedAbout the From…
  • Families Matter in Mental Health: An Education and Support Program -- Halifax

    26 Nov 2014 | 3:30 am
    Begins Tuesday, January 13th, 2015, at 6:30 pmBayers Road Community Mental HealthBayers Road Centre7071 Bayers Road, Suite 109Halifax, Nova ScotiaFor further information and to register, please call the Healthy Minds Cooperative at 902-404-3504, or send an email to hmnavigator@eastlink.ca.Please click on the image to magnify it.To download a PDF version of the above poster, please click here.
  • Getting Mental Health Crisis Support in Nova Scotia

    23 Nov 2014 | 4:00 am
    Call (902) 429-8167 or 1-888-429-8167 (toll free)The Mental Health Mobile Crisis Team (MHMCT) provides intervention and short term crisis management for children, youth and adults experiencing a mental health crisis. They offer 24/7 telephone intervention throughout Nova Scotia - (902) 429-8167 or 1-888-429-8167 (toll free) - and mobile response (1:00 pm to 1:00 am) in areas served by Halifax Regional Police including Halifax, Dartmouth and Bedford.Note that this video is two years old and it does not mention the 24/7 telephone crisis intervention service that is now available throughout Nova…
  • How to refer someone to the Nova Scotia Early Psychosis Program

    23 Nov 2014 | 3:30 am
    From the Nova Scotia Early Psychosis Program (NSEPP) website:Because NSEPP is located in Halifax, within the largest of the Nova Scotia health regions; Capital Health, the program provides direct clinical services to residents of the Capital Health district.Referrals to NSEPP can be made by anyone, including mental health care professionals, family physicians, community agencies, educators and school counselors, family members, friends and any young person who suspects they may be suffering from a first episode of psychosis.Criteria for referral of individuals who reside in the Capital Health…
  • Assistance with navigating mental health services in the Capital Health district

    23 Nov 2014 | 3:00 am
    404-3504 ext. 201From the Healthy Minds Cooperative's February 2013 newsletter:NavigationGoing through the mental health system can be like trying to find your way through a maze. Navigation is a service that the Healthy Minds Cooperative provides that helps guide people living with a mental illness, and their families, to connect with support services in the community. The Navigator can answer your questions and concerns about:Services in the communitySupport groupsPrograms and workshopsReferral ServicesAdvocacyWeb-based resourcesFor more information about navigation, please call (902)…
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    schizophrenic.com

  • Excess protein in brain could trigger schizophrenia

    M Tyler
    24 Nov 2014 | 8:40 am
    The area of the brain responsible for conscious thought, spatial reasoning and language development could be compromised by the overabundance of a particular protein in people with schizophrenia, new research suggests. A study from Rutgers University found that too much protein expressed by the NOS1AP gene can cause abnormalities in the structure and function of the neocortex, resulting in poor connections between nerve cells. Bonnie Firestein, professor in the Department of Cell Biology and Neuroscience at Rutgers, and her colleagues tested rats who had varying levels of NOS1AP. "When the…
  • Fish oil supplements may help prevent psychosis

    M Tyler
    20 Nov 2014 | 8:20 am
    A small study presented at the Early Psychosis Conference in Tokyo suggests that fish oil may give protective benefits against psychosis in young people at risk for the condition. Fish oil is rich in omega-3 fatty acids, which have been linked to better brain health and potentially the ability to ward off dementia. Patients in the study received four capsules of fish oil per day with two types of omega-3 fatty acids: 700 milligrams of EPA and 480 milligrams of DHA. The participants also took 7.6 milligrams of vitamin E. Another control group of patients received placebo pills, and both groups…
  • Community prevention program for schizophrenia drops psychosis-related hospitalizations

    M Tyler
    11 Nov 2014 | 1:32 pm
    An intervention program aimed at identifying high-risk cases of schizophrenia has helped dramatically reduce hospitalizations for psychosis in Portland, Maine. The Portland Identification and Early Referral (PIER) Program accomplished a 26-percent reduction in psychosis-related hospital admissions compared with control areas, Medscape reports. The program helped to educate more than 7200 physicians, school counselors and mental health practitioners on spotting the signs of psychosis in young people who were at risk. Individuals who met certain risk criteria were given Family-aided Assertive…
  • Auditory processing can gives clues about schizophrenia

    M Tyler
    6 Nov 2014 | 2:41 pm
    The use of electroencephalography (EEG) testing could help identify signs of schizophrenia, according to new research. Two new studies suggest that individuals with schizophrenia have impaired auditory processing and that EEG testing can produce results that reveal these impairments. As Medscape reports, this type of testing could be used to measure the severity of a person's condition, or perhaps point physicians toward cognitive exercises that could help these patients strengthen their auditory processing faculties. Taking the 'guesswork out of a diagnosis' According to Gregory A. Light,…
  • Mental illness in children and youth has leveled off, large Canadian study suggests

    M Tyler
    3 Nov 2014 | 1:06 pm
    While media tends to reinforce the idea that mental disorders are on the rise, this probably isn't the case for children and youth, says Dr. Ian Colman in a new study from the University of Ottawa. Dr. Colman and his team recently looked into data from the National Longitudinal Survey of Children and Youth, seeking to better understand whether or not symptoms of mental illness are indeed increasing - specifically hyperactivity, depression, anxiety, aggression and suicidal thinking or behavior. The participants, which included over 31,000 children between the ages of 10 and 15, were asked…
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