Schizophrenia

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  • Researchers find dozens of genetic links to schizophrenia

    Schizophrenia News
    23 Jul 2014 | 1:12 pm
    In a new study, researchers identified 108 locations on the human genome that are tied to schizophrenia risk by comparing the genomes of more than 80,000 people with and without the disorder.
  • Apathy But Not Diminished Expression in Schizophrenia Is Associated With Discounting of Monetary Rewards by Physical Effort

    Schizophrenia Bulletin - Advance Access
    Hartmann, M. N., Hager, O. M., Reimann, A. V., Chumbley, J. R., Kirschner, M., Seifritz, E., Tobler, P. N., Kaiser, S.
    22 Jul 2014 | 8:09 am
    Negative symptoms in schizophrenia have been grouped into the 2 factors of apathy and diminished expression, which might be caused by separable pathophysiological mechanisms. Recently, it has been proposed that apathy could be due to dysfunctional integration of reward and effort during decision making. We asked whether apathy in particular is associated with stronger devaluation ("discounting") of monetary rewards that require physical effort. Thirty-one patients with schizophrenia and 20 healthy control participants performed a computerized effort discounting task in which they could choose…
  • Existence of monomer and dimer forms of mGluR5, under reducing conditions in studies of postmortem brain in various psychiatric disorders

    Schizophrenia Research
    S. Hossein Fatemi, Timothy D. Folsom
    15 Jul 2014 | 5:00 pm
  • Jumping to Conclusions, Neuropsychological Functioning, and Delusional Beliefs in First Episode Psychosis

    Schizophrenia Bulletin - Advance Access
    Falcone, M. A., Murray, R. M., Wiffen, B. D. R., O'Connor, J. A., Russo, M., Kolliakou, A., Stilo, S., Taylor, H., Gardner-Sood, P., Paparelli, A., Jichi, F., Di Forti, M., David, A. S., Freeman, D., Jolley, S.
    22 Jul 2014 | 8:09 am
    Background: The "jumping to conclusions" (JTC) data-gathering bias is implicated in the development and maintenance of psychosis but has only recently been studied in first episode psychosis (FEP). In this study, we set out to establish the relationship of JTC in FEP with delusions and neuropsychological functioning. Methods: One hundred and eight FEP patients and 101 age-matched controls completed assessments of delusions, general intelligence (IQ), working memory (WM), and JTC (the probabilistic reasoning "beads" task). Results: Half the FEP participants jumped to conclusions on at least 1…
  • Study offers new clues into schizophrenia's genetic code

    schizophrenic.com
    Mara Tyler
    22 Jul 2014 | 12:09 pm
    The largest genomic study of schizophrenia patients suggests there may be over 100 chromosomal sites implicated in the disorder, but about 80 of them haven't been reported until now. The study, which comes from researchers at the Broad Institute of MIT and Harvard, reveals that some gene variants responsible for the development of schizophrenia are related to functions like dopamine release in the brain, while others might be associated with things like immune system or heavy smoking. "Some are very familiar genes expressed in nerve cells, and some are results where you scratch your head and…
 
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    MedWorm: Schizophrenia

  • Science News » Schizophrenia’s Genetic “Skyline” Rising

    22 Jul 2014 | 4:03 pm
    The largest genomic dragnet of any psychiatric disorder to date has unmasked 108 chromosomal sites harboring inherited variations in the genetic code linked to schizophrenia, 83 of which had not been previously reported. (Source: National Institute of Mental Health)MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
  • Vitamin D Blog: Low D Levels in Schizophrenia

    22 Jul 2014 | 3:43 pm
    (MedPage Today) -- Vitamin D-deficient individuals are more than twice as likely to be diagnosed with schizophrenia compared with people with levels normally considered sufficient, a meta-analysis found. (Source: MedPage Today Psychiatry)
  • New Schizophrenia Genes IdentifiedNew Schizophrenia Genes Identified

    22 Jul 2014 | 2:16 pm
    Eighty-three novel genes linked to schizophrenia, including one that also raises the risk for bipolar disorder and alcoholism, have been identified. Medscape Medical News (Source: Medscape Psychiatry Headlines)
  • Schizophrenia has many genetic links, study says

    22 Jul 2014 | 1:12 pm
    NEW YORK - More than 100 locations on the human genome may play a role in a person’s risk of developing schizophrenia, according to a new study. (Source: Reuters: Health)
  • More than 100 genes linked to schizophrenia

    22 Jul 2014 | 12:55 pm
    Scientists have zeroed in on more than 100 genes linked to risk for the psychiatric disorder, which may help lead to more effective treatments (Source: Health News: CBSNews.com)
 
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    About.com Schizophrenia: What's Hot Now

  • Living With Schizophrenia

    schizophrenia.guide@about.com
    24 Jul 2014 | 4:14 am
    Schizophrenia is a chronic disease, and you should plan for times of remission and times of relapse. Even in remission, your residual symptoms (the symptoms you continue to have even when you’re relatively well) will effect all aspects of your life. This article from your About Guide to Schizophrenia gives you concrete suggestions to help you improve you independent living skills and social relationships.
  • Schizophrenia Symptoms and Diagnosis

    schizophrenia.guide@about.com
    24 Jul 2014 | 4:14 am
    What are the main symptoms of schizophrenia? How is a diagnosis of schizophrenia made?
  • The Positive and Negative Symptoms of...

    schizophrenia.guide@about.com
    24 Jul 2014 | 4:14 am
    Are you having experiences that seem unreal? Are you concerned about strange behavior in a loved one? Learn to understand and describe the symptoms of schizophrenia, so that you can communicate them to a doctor.
  • What Causes Schizophrenia?

    schizophrenia.guide@about.com
    24 Jul 2014 | 4:14 am
    Genes play a key role in developing schizophrenia, although they can't predict the illness on their own. Genes seem to make a person vulnerable to another factor that brings the illness on. Page 2.
  • Who Gets Schizophrenia?

    schizophrenia.guide@about.com
    24 Jul 2014 | 4:14 am
    Although the overall incidence of schizophrenia in the United States is close to 1%, different groups have a greater or lesser likelihood of developing the illness. This article from your About Guide to Schizophrenia reviews the incidence of schizophrenia among different groups of people, which scientists are using as clues to help find the cause.
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    About.com Schizophrenia: Most Popular Articles

  • Psychosis

    24 Jul 2014 | 5:45 am
    Definition of the term, psychosis
  • Decompensate

    24 Jul 2014 | 5:45 am
    Definition of the term, decompensate.
  • The Positive and Negative Symptoms of...

    24 Jul 2014 | 5:45 am
    Are you having experiences that seem unreal? Are you concerned about strange behavior in a loved one? Learn to understand and describe the symptoms of schizophrenia, so that you can communicate them to a doctor.
  • Patient's perspective: A Beautiful Mind (the...

    24 Jul 2014 | 5:45 am
    A patient's perspective: A Beautiful Mind, the movie
  • Atypical Antipsychotic Drugs Used to Treat...

    24 Jul 2014 | 5:45 am
    In the early 1990s a new class of drugs were developed to treat the psychotic symptoms of schizophrenia. These drugs, the atypical antipsychotics, have proven generally as effective as the antispychotics developed decades earlier, with fewer extrapyrimidal side effects. This list of the atypical antipsychotics provides links to drug safety information from the drug manufacturers' websites.
 
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    Schizophrenia Bulletin - Advance Access

  • Jumping to Conclusions, Neuropsychological Functioning, and Delusional Beliefs in First Episode Psychosis

    Falcone, M. A., Murray, R. M., Wiffen, B. D. R., O'Connor, J. A., Russo, M., Kolliakou, A., Stilo, S., Taylor, H., Gardner-Sood, P., Paparelli, A., Jichi, F., Di Forti, M., David, A. S., Freeman, D., Jolley, S.
    22 Jul 2014 | 8:09 am
    Background: The "jumping to conclusions" (JTC) data-gathering bias is implicated in the development and maintenance of psychosis but has only recently been studied in first episode psychosis (FEP). In this study, we set out to establish the relationship of JTC in FEP with delusions and neuropsychological functioning. Methods: One hundred and eight FEP patients and 101 age-matched controls completed assessments of delusions, general intelligence (IQ), working memory (WM), and JTC (the probabilistic reasoning "beads" task). Results: Half the FEP participants jumped to conclusions on at least 1…
  • Does Population Density and Neighborhood Deprivation Predict Schizophrenia? A Nationwide Swedish Family-Based Study of 2.4 Million Individuals

    Sariaslan, A., Larsson, H., D'Onofrio, B., Langstrom, N., Fazel, S., Lichtenstein, P.
    22 Jul 2014 | 8:09 am
    People living in densely populated and socially disorganized areas have higher rates of psychiatric morbidity, but the potential causal status of such factors is uncertain. We used nationwide Swedish longitudinal registry data to identify all children born 1967–1989 (n = 2361585), including separate datasets for all cousins (n = 1715059) and siblings (n = 1667894). The nature of the associations between population density and neighborhood deprivation and individual risk for a schizophrenia diagnosis was investigated while adjusting for unobserved familial risk factors (through cousin…
  • Apathy But Not Diminished Expression in Schizophrenia Is Associated With Discounting of Monetary Rewards by Physical Effort

    Hartmann, M. N., Hager, O. M., Reimann, A. V., Chumbley, J. R., Kirschner, M., Seifritz, E., Tobler, P. N., Kaiser, S.
    22 Jul 2014 | 8:09 am
    Negative symptoms in schizophrenia have been grouped into the 2 factors of apathy and diminished expression, which might be caused by separable pathophysiological mechanisms. Recently, it has been proposed that apathy could be due to dysfunctional integration of reward and effort during decision making. We asked whether apathy in particular is associated with stronger devaluation ("discounting") of monetary rewards that require physical effort. Thirty-one patients with schizophrenia and 20 healthy control participants performed a computerized effort discounting task in which they could choose…
  • Early Developmental Disturbances of Cortical Inhibitory Neurons: Contribution to Cognitive Deficits in Schizophrenia

    Volk, D. W., Lewis, D. A.
    22 Jul 2014 | 1:03 am
    Cognitive dysfunction is a disabling and core feature of schizophrenia. Cognitive impairments have been linked to disturbances in inhibitory (gamma-aminobutyric acid [GABA]) neurons in the prefrontal cortex. Cognitive deficits are present well before the onset of psychotic symptoms and have been detected in early childhood with developmental delays reported during the first year of life. These data suggest that the pathogenetic process that produces dysfunction of prefrontal GABA neurons in schizophrenia may be related to altered prenatal development. Interestingly, adult postmortem…
  • Cognitive Mechanisms of Change in Delusions: An Experimental Investigation Targeting Reasoning to Effect Change in Paranoia

    Garety, P., Waller, H., Emsley, R., Jolley, S., Kuipers, E., Bebbington, P., Dunn, G., Fowler, D., Hardy, A., Freeman, D.
    21 Jul 2014 | 8:31 pm
    Background: Given the evidence that reasoning biases contribute to delusional persistence and change, several research groups have made systematic efforts to modify them. The current experiment tested the hypothesis that targeting reasoning biases would result in change in delusions. Methods: One hundred and one participants with current delusions and schizophrenia spectrum psychosis were randomly allocated to a brief computerized reasoning training intervention or to a control condition involving computer-based activities of similar duration. The primary hypotheses tested were that the…
 
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    Schizophrenia Society of Saskatchewan

  • Family Members and Caregiver’s Survey

    Schizophrenia Society of Saskatchewan
    17 Jul 2014 | 12:42 pm
    Are you a family member or caregiver to someone with schizophrenia,bipolar disorder, or other related mental illness? The Schizophrenia Society of Canada is doing research into the experiences of caregivers, and would like your feedback. If you are interested in taking part in this very important research, please click here to proceed to the Schizophrenia Society of Canada research page. Thank you for time and insight!
  • SSC Award Applications are now being accepted – Deadline is September 12, 2014

    Schizophrenia Society of Saskatchewan
    17 Jul 2014 | 12:37 pm
    The Schizophrenia Society of Canada is now accepting applications for their annual awards. Click here to learn more!
  • Schizophrenia Society Annual Awards – Nomination Forms

    Schizophrenia Society of Saskatchewan
    22 Jun 2014 | 2:33 pm
    The Schizophrenia Society of Saskatchewan will be handing out awards again this year September our AGM (date pending). If you are interested in nominating someone for any of the following awards, please download the appropriate form and return it to the Schizophrenia Society of Saskatchewan by Monday, July 28th, 2014. Schizophrenia Society of Saskatchewan Award Nomination Form 2014 Community Spirit Award - This award recognizes a business, corporation or organization for their outstanding community spirit in supporting the SSS in their mission to improve the quality of life of those affected…
  • Letter to Minister MacKay, Minister of Justice

    Schizophrenia Society of Saskatchewan
    23 Oct 2013 | 8:14 am
    October 15, 2013 Honourable Peter MacKay Minister of Justice/ Attorney General of Canada House of Commons Ottawa, Ontario K1A 0A6 Dear Minister MacKay, On behalf of the eleven national professional health organizations supporting this letter, we first would like to take this opportunity to congratulate you on assuming the role of Minister of Justice and Attorney General of Canada. This position and its responsibilities have implications for all Canadians. We look forward to supporting your work in developing sound, evidenced-based legislation that will serve to both protect the public and…
  • Partnership Program Members Make the Airwaves

    Schizophrenia Society of Saskatchewan
    10 Oct 2013 | 2:40 pm
    As part of Mental Health Awareness week, members of our Partnership Program have made appearances on the local media! Way to go team! Read about Saskatoon’s Matthew Proctor’s appearance on 650 CKOM. And check out Curtis Harman on Global TV.
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    Schizophrenia News -- ScienceDaily

  • Are state Medicaid policies sentencing people with mental illnesses to prison?

    22 Jul 2014 | 11:26 am
    A link between Medicaid policies on antipsychotic drugs and incarceration rates for schizophrenic individuals has been uncovered by a new study. Researchers found that states requiring prior authorization for atypical antipsychotics had less serious mental illness overall but higher shares of inmates with psychotic symptoms than the national average. The study concluded that prior authorization of atypical antipsychotics was associated with a 22 percent increase in the likelihood of imprisonment, compared with the likelihood in a state without such a requirement.
  • Vitamin D deficiency raises risk of schizophrenia diagnosis

    22 Jul 2014 | 11:25 am
    Vitamin D-deficient individuals are twice as likely to be diagnosed with schizophrenia as people who have sufficient levels of the vitamin, according to a new study. Vitamin D helps the body absorb calcium and is needed for bone and muscle health. The skin naturally produces this vitamin after exposure to sunlight. People also obtain smaller amounts of the vitamin through foods, such as milk fortified with vitamin D. More than 1 billion people worldwide are estimated to have deficient levels of vitamin D due to limited sunshine exposure.
  • Schizophrenia's genetic 'skyline' rising as genetic code linked to illness grows

    22 Jul 2014 | 6:17 am
    The largest genomic dragnet of any psychiatric disorder to date has unmasked 108 chromosomal sites harboring inherited variations in the genetic code linked to schizophrenia, 83 of which had not been previously reported. By contrast, the 'skyline' of such suspect variants associated with the disorder contained only 5 significant peaks in 2011. Researchers combined data from all available schizophrenia genetic samples to boost statistical power high enough to detect subtle effects on risk.
  • Epigenetic tie to neuropsychiatric disorders found

    21 Jul 2014 | 11:22 am
    Dysfunction in dopamine signaling profoundly changes the activity level of about 2,000 genes in the brain's prefrontal cortex and may be an underlying cause of certain complex neuropsychiatric disorders, such as schizophrenia, according to scientists. This epigenetic alteration of gene activity in brain cells that receive this neurotransmitter showed for the first time that dopamine deficiencies can affect a variety of behavioral and physiological functions regulated in the prefrontal cortex.
  • Antipsychotic drugs linked to slight decrease in brain volume

    18 Jul 2014 | 2:20 pm
    A new study has confirmed a link between antipsychotic medication and a slight, but measureable, decrease in brain volume in patients with schizophrenia. For the first time, researchers have been able to examine whether this decrease is harmful for patients' cognitive function and symptoms, and noted that over a nine year follow-up, this decrease did not appear to have any effect.
 
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    Schizophrenia Society of Nova Scotia

  • The "From Recovery to Discovery" Mental Health Peer Support Group - Halifax

    24 Jul 2014 | 4:00 am
    TODAY, July 24th, 6:30 pmMeetingsEvery Thursday Evening6:30 pm to 8:30 pmCommunity RoomAtlantic Superstore – Barrington Street 1075 Barrington StreetHalifax, Nova Scotia Plenty of free parking!The Atlantic Superstore – Barrington Street is on the 3, 7, 9, and 41 Metro Transit bus routes.The From Recovery to Discovery Mental Health Peer Support Group is open to anyone affected by any type of mental illness, and this includes family members and friends.Free! Thursday, July 24th, 2014, 6:30 pmAn Interactive Conversation about the Entrepreneurs with Disabilities NetworkwithArchie…
  • Nova Scotia Certified Peer Support Specialist Program - Brochure

    23 Jul 2014 | 3:30 am
    Please click on an image to enlarge it.To download a PDF version of the above brochure, please click here.Also see:Healthy Minds CooperativeHealthy Minds Cooperative - Brochure (PDF)
  • Families Matter in Mental Health: An Education and Support Program -- Halifax Regional Municipality

    22 Jul 2014 | 3:30 am
    Please click on the image to magnify it.To download a PDF version of the above flyer, please click here.To download the Families Matter in Mental Health provincial brochure (PDF), please click here.Also see:Supporting Families in Recovery - Capital Health Addictions and Mental Health ProgramFamilies Matter in Mental Health: An Education and Support Program -- Nova Scotia
  • Supporting Families in Recovery - Capital Health Addictions and Mental Health Program

    21 Jul 2014 | 3:30 am
    Please click on the image to magnify it.A PDF version of the above poster can be downloaded by clicking here.Also see:Capital Health Addictions and Mental Health ProgramFamilies Matter in Mental HealthMental Health Foundation of Nova ScotiaSchizophrenia Society of Nova Scotia Healthy Minds Cooperative
  • How to refer someone to the Nova Scotia Early Psychosis Program

    21 Jul 2014 | 3:00 am
    From the Nova Scotia Early Psychosis Program (NSEPP) website:Because NSEPP is located in Halifax, within the largest of the Nova Scotia health regions; Capital Health, the program provides direct clinical services to residents of the Capital Health district.Referrals to NSEPP can be made by anyone, including mental health care professionals, family physicians, community agencies, educators and school counselors, family members, friends and any young person who suspects they may be suffering from a first episode of psychosis.Criteria for referral of individuals who reside in the Capital Health…
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    schizophrenic.com

  • Study offers new clues into schizophrenia's genetic code

    Mara Tyler
    22 Jul 2014 | 12:09 pm
    The largest genomic study of schizophrenia patients suggests there may be over 100 chromosomal sites implicated in the disorder, but about 80 of them haven't been reported until now. The study, which comes from researchers at the Broad Institute of MIT and Harvard, reveals that some gene variants responsible for the development of schizophrenia are related to functions like dopamine release in the brain, while others might be associated with things like immune system or heavy smoking. "Some are very familiar genes expressed in nerve cells, and some are results where you scratch your head and…
  • Schizophrenics lose brain volume faster with antipsychotic medications

    Mara Tyler
    21 Jul 2014 | 1:13 pm
    Taking antipsychotics is associated with a decrease in brain volume for schizophrenia patients, reports a new study in PLOS One. The loss of volume occurs from a decrease in brain cells and connections, which can happen naturally with age. Yet people with schizophrenia lose brain volume at a faster rate, said the University of Cambridge researchers. So should schizophrenia patients give up their antipsychotic medications because of potential brain volume loss? Not at all, said study author Dr. Graham Murray. "It's important to stress that the loss of brain volume doesn't appear to have any…
  • Memory impairment in schizophrenia may be due to faulty 'noise filter'

    Mara Tyler
    15 Jul 2014 | 3:20 pm
    The inability to filter out stimuli could be linked to the memory problems often associated with schizophrenia, a new study suggests. Researchers from Columbia University found that a glitch in this type of filtering process can cause significant impairments in the ability to control working memory, the team wrote in the journal Biological Psychiatry. "Our assumption was that understanding the impairments in the component processes of working memory - the ability to hold and manipulate information in the mind - among patients with schizophrenia could be fundamental to understanding not only…
  • Maternal blood inflammation linked to schizophrenia

    Mara Tyler
    8 Jul 2014 | 11:59 am
    The presence of early gestational C-reactive protein, which is an inflammation marker, in a mother's blood could indicate a greater schizophrenia risk for her offspring, report researchers in the American Journal of Psychiatry. Using data from the Finnish Prenatal Study of Schizophrenia, Columbia researchers and their Finland colleagues tested for the presence of C-reactive protein in the maternal blood of 777 offspring with schizophrenia. They then compared the findings with the blood of 777 control subjects. Increased c-reactive protein associated with schizophrenia Researchers found that…
  • Sleep deprivation leads to schizophrenia-like symptoms

    Mara Tyler
    7 Jul 2014 | 1:45 pm
    For healthy people, just 24 hours of sleep deprivation can lead to symptoms that resemble schizophrenia, new research reports. The findings may help researchers create a model that assists in the development of drugs to treat psychosis-related conditions. Chaos in the brain Scientists from the University of Bonn, King's College London and the Department of Psychiatry and Psychotherapy at the University of Bonn Hospital recruited 24 healthy subjects between the ages of 18 and 40 for the study. During the first part of the trial, participants slept normally in a laboratory. One week later, they…
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    Schiz Life

  • The 12 Core Functions: Your Therapist and Treatment Path

    Schiz Life
    20 Jul 2014 | 5:43 am
    The 12 Core Functions: Your Therapist and Treatment PathA sad reality is that many people dealing with the symptoms of schizophrenia simply fail to receive treatment.  There are lots of various reasons why this can happen, but one of the reasons is a resistance and fear in not understanding how treatment will transpire.  This article is meant to give the reader a general overview of what the therapist is thinking and the guidelines they follow to perform their task.  Your treatment will be personalized and tailored specifically to your experiences, symptoms, and receptiveness, but it will…
  • Schizophrenia Spectrum Disorders

    Schiz Life
    25 May 2014 | 1:52 pm
    What is schizophrenia spectrum disorder? How is it diagnosed and treated? A better understanding of this disorder might be derived from an understanding of the terms used to identify it.Schizophrenia is a mental disorder characterized by reduced emotional expression, abnormal social behavior and the inability to distinguish what is real and what isn’t. Persons with schizophrenia might talk about hearing voices, experience hallucinations, and suffer delusions.Spectrum refers to a range of linked conditions sometimes extending to include singular symptoms and disorders, as they relate to…
  • Schizophrenia Risk Factors

    Schiz Life
    25 May 2014 | 1:39 pm
    Schizophrenia is a chronic mental disorder that adversely affects about 1 per cent of the global population. It is commonly described as someone being delusional, paranoid, and hallucinating, but that’s only one type of schizophrenia. Schizophrenia can occur at any age, but it tends to first progress between adolescence and early adulthood, normally between the ages of 16 – 30 years. It rarely occurs before adolescence or after age 45. It is more likely to worsen if left untreated. The illness itself cannot be cured but with sufficient medication, the symptoms can be controlled.
  • Movies About Schizophrenia

    Schiz Life
    24 May 2014 | 2:05 pm
    Schizophrenia is a devastating mental illness which affects approximately one in a hundred people. It usually strikes first in the early teenage years and involves hallucinations and delusions. It is one of those disorders that people find bizarre yet fascinating to learn about. Over the years, Hollywood has used the opportunity to bring top quality movies that depict this illness and at the same time shed some light on the severity to which it can affect persons.Why Movies About Schizophrenia Are Intriguing To ManyUsually, movies about schizophrenia reconstruct the mental experiences of the…
  • Who Discovered Schizophrenia?

    Schiz Life
    28 Apr 2014 | 2:31 pm
    Schizophrenia is currently the most enigmatic and dramatic disease in the psychiatric spectrum. While there are plenty of known aspects about it, the truth is that understanding it is a very complicated task. Many symptoms are known, but researching it from the outside and really truly comprehending the experience is a real challenge. The good news is that current research studies have led to numerous discoveries and advancements in this field. Schizophrenia is no longer impossible to diagnose. However, at this time there is no permanent cure. We can manage the symptoms and often prevent…
 
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